ACADEMIC TRAINING
| 2008- | Postdoc(Biostatistics) | Penn State College of Medicine |
| 1997-2000 | Ph.D.(Engineering Mechanics) | Dalian University of Technology, China |
| 1994-1997 | MS (Computer Science) | Dalian University of Technology, China |
| 1990-1994 | BS (Computer Science) | Dalian University of Technology, China |
RESEARCH INTERESTS
- Statistical Genetics and Genomics
- Systems Biology
- Bioinformatics
- Genetic Epidemiology
PAPERS
- [1]. Zhongxian Chi, Zhong Wang. Multimedia presentation system and application. Journal of Dalian university of technology, Vol35, no.6 (1995):894-898.
- [2]. Zhong-xian Chi, Zhong Wang, Shuli Cui. Method to translate Openwin V3.0 into Chinese edition. Journal of Dalian university of technology, Vol36, no.6 (1996): 741-744.
- [3]. Wang Zhong, Zhongxian Chi, Shuli Cui. Dynamic translation of GUI of client software of Openwin. Journal of Dalian university of technology, Vol36, no.6 (1996): 745-749.
- [4]. Zhongxian Chi, Zhong Wang, Runbin Liu, Lida Wang. Design and implementation of multimedia spatial database management system (MSDBMS). Journal of Dalian university of technology, Vol37, no.5, (1997): 600-602.
- [5]. Zhongxian Chi, Zhong Wang, Xiaoshi Li, Runbin Liu. Research on a kind of restructured MIS model technology. Journal of Dalian university of technology, Vol38, no.1, (1998): 105-108.
- [6]. Zhong Wang, Zhongxian Chi, Chenguang Wang. Hypermedia management system on distributed object. Journal of Dalian university of technology, Vol39, no.4, (1999):572-576.
- [7]. Zhong Wang, Zhongxian Chi, Chenguang Wang. MAC: component reuse architecture based on multi-agent adapter. In: Proc. of Technology of Object-Oriented Languages and Systems, TOOL31, Oct 1999, Published by IEEE Computer Society.
- [8]. Zhong Wang, Zhongxian Chi . Design of clinical instruments integration system in multi C/S model. Journal of Mini-Micro System. Vol21, no.4, (2000):103-105.
- [9]. Zhongxian Chi, Xiaorui Quan , Chenguang Wang , Zhong Wang. Using multiagent adapter to design component software. Journal of Mini-Micro System. Vol22, no.5, (2001):608-610
- [10]. Zhongxian Chi, Abdi KERIM, Yong-qiang GAO , Zhong Wang . A component reuse method based on multiagent adapter. Journal of Dalian university of technology, Vol42, no.1, (2002).
- [11]. Zhongxian Chi, Zhanchang Wang , Ruiwei Wang , Zhong Wang. Research on Using Spatial Object Model to Integrate Data on Web, Journal of Mini-Micro System. Vol23 no.10, (2002):1185-1188
- [12]. Jiang Ning, Gao Jing, Wang Zhong. Using Spatial Object Model to Implement AM/FM/GIS System on Web. Journal of Computer Engineering and Applications. Vol 20, (2002).
- [13]. Ning Li, Timothy McMurry, Arthur Berg, Zhong Wang, Scott A. Berceli, and Rongling Wu. "Functional clustering of periodic transcriptional profiles through ARMA (p, q)." PloS one 5, no. 4 (2010): e9894.
- [14]. Yao Li, Louie Wu, Zhong Wang, Gang Chen, Rongling Wu. "Modeling the Aneuploidy Control of Cancer." BMC Cancer 10 (2010).
- [15]. Chenguang Wang, Zhong Wang, Jiangtao Luo, Qin Li, Yao Li, Kwangmi Ahn, Daniel R. Prows, and Rongling Wu. "A model for transgenerational imprinting variation in complex traits." PLoS One 5, no. 7 (2010): e11396.
- [16]. Zhong Wang, Tian Liu, Zhenwu Lin, John Hegarty, Walter A. Koltun, and Rongling Wu. "A general model for multilocus epistatic interactions in case-control studies." PloS one 5, no. 8 (2010): e11384.
- [17]. Yao Li, Changxing Ma, Zhong Wang, Gang Chen, Kwangmi Ahn, Philip Lazarus, and Rongling Wu. "A disequilibrium model for detecting genetic mutations for cancer." Journal of theoretical biology 265, no. 3 (2010): 218-224.
- [18]. Arthur Berg, Ning Li, C. F. Tong, Zhong Wang, Scott A. Berceli, and R. L. Wu. "Functional mapping of expression quantitative trait loci that regulate oscillatory gene expression." Methods Mol Biol 734 (2011): 241-255.
- [19]. Guifang Fu, Jiangtao Luo, Arthur Berg, Zhong Wang, Jiahan Li, Kiranmoy Das, Runze Li, and Rongling Wu. "A dynamic model for functional mapping of biological rhythms." Journal of biological dynamics 5, no. 1 (2011): 84-101.
- [20]. Kiranmoy Das, Jiahan Li, Zhong Wang, Chunfa Tong, Guifang Fu, Yao Li, Meng Xu et al. "A dynamic model for genome-wide association studies." Human genetics 129, no. 6 (2011): 629-639.
- [21]. Tian Liu, A. Thalamuthu, J. J. Liu, C. Chen, Zhong Wang, and Rongling Wu. "Asymptotic distribution for epistatic tests in case-control studies. Genomics 2011:98(2): 145-151.
- [22]. Rongling Wu, Chunfa Tong, Zhong Wang, David Mauger, Kelan Tantisira, Stanley J. Szefler, Vernon M. Chinchilli, and Elliot Israel. "A conceptual framework for pharmacodynamic genome-wide association studies in pharmacogenomics." Drug discovery today 16, no. 19 (2011): 884-890.
- [23]. Zhenwu Lin, John P. Hegarty, Arthur Berg, Zhong Wang, Ashley A. Kelly, Yunhua Wang, Lisa S. Poritz, Rongling Wu, and Walter A. Koltun. "DLG5 P1371Q is associated with inflammatory bowel disease and complementary to R30Q in disease susceptibility." Swiss medical weekly 141 (2011): w13290.
- [24]. Chunfa Tong, Bo Zhang, Zhong Wang, Meng Xu, Xiaoming Pang, Jingna Si, Minren Huang, and Rongling Wu. "Multiallelic epistatic model for an out-bred cross and mapping algorithm of interactive quantitative trait loci." BMC plant biology 11, no. 1 (2011): 148.
- [25]. Rongling Wu, Jiguo Cao, Zhongwen Huang, Zhong Wang, Junyi Gai, and Eduardo Vallejos. "Systems mapping: how to improve the genetic mapping of complex traits through design principles of biological systems." BMC systems biology 5, no. 1 (2011): 84.
- [26]. Guifang Fu, Zhong Wang, Jiahan Li, and Rongling Wu. "A mathematical framework for functional mapping of complex phenotypes using delay differential equations." Journal of theoretical biology 289 (2011): 206-216.
- [27]. Arthur Berg, Ning Li, C. F. Tong, Zhong Wang, Scott A. Berceli, and R. L. Wu. "Functional mapping of expression quantitative trait loci that regulate oscillatory gene expression." Methods Mol Biol 734 (2011): 241-255.
- [28]. Kiranmoy Das, Jiahan Li, Guifang Fu, Zhong Wang, and Rongling Wu. "Genome-Wide Association Studies for Bivariate Sparse Longitudinal Data." Human Heredity 72, no. 2 (2011): 110-120.
- [29]. Huber-Keener, Kathryn J., Xiuping Liu, Zhong Wang, Yaqun Wang, Willard Freeman, Song Wu, Maricarmen D. Planas-Silva et al. "Differential Gene Expression in Tamoxifen-Resistant Breast Cancer Cells Revealed by a New Analytical Model of RNA-Seq Data". PloS one 2012:7(7): e41333.
- [30]. Yafei Lu, Xiaoxia Yang, Chunfa Tong, Xin Li, Sisi Feng, Zhong Wang, Xiaoming Pang et al. "A multivalent three-point linkage analysis model of autotetraploids". Briefings in Bioinformatics (2012).
- [31]. Kiranmoy Das, Jiahan Li, Guifang Fu, Zhong Wang, Runze Li, and Rongling Wu. "Dynamic semiparametric Bayesian models for genetic mapping of complex trait with irregular longitudinal data." Statistics in Medicine (2012).
- [32]. Shen Zhu, You-Zhi Cao, Cong Jiang, Bi-Yue Tan, Zhong Wang, Sisi Feng, Liang Zhang et al. "Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-evolution." BMC genomics 13, no. 1 (2012): 382.
- [33]. Chunfa Tong, Lianying Shen, Yafei Lv, Zhong Wang, Xiaoling Wang, Sisi Feng, Xin Li, Yihan Sui, Xiaoming Pang, and Rongling Wu. "Structural mapping: how to study the genetic architecture of a phenotypic trait through its formation mechanism." Briefings in Bioinformatics (2012).
- [34]. Sheng Zhu, Zhong Wang, Jianxin Wang, Yaqun Wang, Ningtao Wang, Zuoheng Wang, Meng Xu et al. "A quantitative model of transcriptional differentiation driving host-pathogen interactions." Briefings in Bioinformatics (2012).
- [35]. Yaqun Wang, Meng Xu, Zhong Wang, Ming Tao, Junjia Zhu, Li Wang, Runze Li, Scott A. Berceli, and Rongling Wu. "How to cluster gene expression dynamics in response to environmental signals." Briefings in bioinformatics 13, no. 2 (2012): 162-174.
- [36]. Chunfa Tong, Zhong Wang, Bo Zhang, Jisen Shi, and Rongling Wu. "3FunMap: full-sib family functional mapping of dynamic traits." Bioinformatics 27, no. 14 (2011): 2006-2008.
- [37]. Chenguang Wang, Zhong Wang, Daniel R. Prows, and Rongling Wu. "A computational framework for the inheritance pattern of genomic imprinting for complex traits." Briefings in bioinformatics 13, no. 1 (2012): 34-45.
- [38]. Xiaoxia Yang, Yafei Lv, Xiaoming Pang, Chunfa Tong, Zhong Wang, Xin Li, Sisi Feng, Christian M. Tobias, and Rongling Wu. "A unifying framework for bivalent multilocus linkage analysis of allotetraploids." Briefings in Bioinformatics (2012).
- [39]. Zhong Wang, Xiaoming Pang, Yafei Lv, Fang Xu, Tao Zhou, Xin Li, Sisi Feng, Jiahan Li, Zhikang Li, and Rongling Wu. "A dynamic framework for quantifying the genetic architecture of phenotypic plasticity." Briefings in bioinformatics (2012).
- [40]. Xiyang Zhao, Chunfa Tong, Xiaoming Pang, Zhong Wang, Yunqian Guo, Fang Du, and Rongling Wu. "Functional mapping of ontogeny in flowering plants." Briefings in bioinformatics 13, no. 3 (2012): 317-328.
- [41]. Wei Hou, Yihan Sui, Zhong Wang, Yaqun Wang, Ningtao Wang, Jingyuan Liu, Yao Li et al. "Systems mapping of HIV-1 infection." BMC genetics 13, no. 1 (2012): 91.
- [42]. Zhong Wang, Zuoheng Wang, Jianxin Wang, Yihan Sui, Jian Zhang, Duanping Liao, and Rongling Wu. "A quantitative genetic and epigenetic model of complex traits." BMC bioinformatics 13, no. 1 (2012): 274.
- [43]. Xiaoming Pang, Zhong Wang, John S. Yap, Jianxin Wang, Junjia Zhu, Wenhao Bo, Yafei Lv et al. "A statistical procedure to map high-order epistasis for complex traits." Briefings in Bioinformatics (2012).
- [44]. Li Zhang, Ruitao Liu, Zhong Wang, Daniel A. Culver, and Rongling Wu. "Modeling haplotype-haplotype interactions in case-control genetic association studies." Frontiers in Genetics 3 (2012).
- [45]. Jingyuan Liu, Zhong Wang, Yaqun Wang, Runze Li, and Rongling Wu. "Frontiers: Model and Algorithm for Linkage Disequilibrium Analysis in a Non-Equilibrium Population." Frontiers in Statistical Genetics And Methodology 3 (2012).
- [46]. Zhong Wang, Jingyuan Liu, Jianxin Wang, Yaqun Wang, Ningtao Wang, Yao Li, Runze Li, and Rongling Wu. "Dynamic modeling of genes controlling cancer stem cell proliferation." Frontiers in Genetics 3 (2012).
- [47]. JianXin Wang, XiaoLi Dong, XiaoMing Pang, YaFei Lv, HuaLin Yi, XiaoXia Yang, Zhong Wang, Song Wu, and RongLing Wu. "Simultaneous estimation of genetic linkage and preferential pairing factor for a triploid population with unphased markers." Chinese Science Bulletin (2012): 1-10.
- [48]. Song Wu, Guifang Fu, Yunmei Chen, Zhong Wang, and Rongling Wu. "Genetic mapping of complex traits by minimizing integrated square errors." BMC genetics 13, no. 1 (2012): 20.
- [49]. Jingyuan Liu, Zhong Wang, Yaqun Wang, Runze Li, and Rongling Wu. "Model and algorithm for linkage disequilibrium analysis in a non-equilibrium population." Frontiers in Genetics 3 (2012).
- [50]. Zhong Wang, Yaqun Wang, Ningtao Wang, Jianxin Wang, Zuoheng Wang, C. Eduardo Vallejos, and Rongling Wu. "Towards a comprehensive picture of the genetic landscape of complex traits." Briefings in Bioinformatics (2012).


